发明名称 |
DISINFECTANT COMPOSITION AND ITS USE IN DENTAL TREATMENT |
摘要 |
The present invention concerns a disinfectant or antimicrobial composition for use in dental treatment, such as treatment and/or prevention of periodontitis, gingivitis or other forms of oral infection. The present Inventor found that microorganisms that infect the dental tissues and cause inflammation thereof, are susceptible to osmotic stress, to such extent that the application of a hypertonic composition is effective in curing or preventing infection and/or inflammations. It was furthermore found that these microorganisms are also susceptible to acidic stress. The present invention therefore provides compositions that induce osmotic stress in microorganisms causing infection of dental tissue when topically applied thereto, preferably osmotic as well as acidic stress. The present invention also concerns the methods and uses involving the compositions of the invention. |
申请公布号 |
US2012328708(A1) |
申请公布日期 |
2012.12.27 |
申请号 |
US201113579577 |
申请日期 |
2011.02.18 |
申请人 |
VAN DER WAAL SUZETTE VERONICA;BRUL STANLEY;DE SOET JOHANNES JACOB;VAN DER SLUIS LUCAS WILHELMUS MARIA;NIKINC PHARMA B.V. |
发明人 |
VAN DER WAAL SUZETTE VERONICA;BRUL STANLEY;DE SOET JOHANNES JACOB;VAN DER SLUIS LUCAS WILHELMUS MARIA |
分类号 |
A61K31/19;A61K33/00;A61P31/00;C07C53/06;C07C53/10;C07C57/10;C07C59/08 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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