发明名称 |
SPIDER SILK PROTEINS AND METHODS FOR PRODUCING SPIDER SILK PROTEINS |
摘要 |
The invention provides an isolated major ampullate spidroin protein, which consists of from 150 to 420 amino acid residues and is defined by the formula REP-CT. REP is a repetitive, N-terminally derived protein fragment having from 80 to 300 amino acid residues. CT is a C-terminally derived protein fragment having from 70 to 120 amino acid residues. The invention further provides an isolated fusion protein consisting of a first protein fragment, which is a major ampullate spidroin protein, and a second protein fragment comprising a fusion partner and a cleavage agent recognition site. The first protein fragment is coupled via said cleavage agent recognition site to the fusion partner. The invention also provides a method of producing a major ampullate spidroin protein and polymers thereof. |
申请公布号 |
US2012329992(A1) |
申请公布日期 |
2012.12.27 |
申请号 |
US201213598119 |
申请日期 |
2012.08.29 |
申请人 |
JOHANSSON JAN;HJAELM GOERAN;STARK MARGARETA;RISING ANNA;GRIP STEFAN;ENGSTROEM WILHELM;HEDHAMMAR MY |
发明人 |
JOHANSSON JAN;HJAELM GOERAN;STARK MARGARETA;RISING ANNA;GRIP STEFAN;ENGSTROEM WILHELM;HEDHAMMAR MY |
分类号 |
C07K14/435;C07K19/00;C12N15/12;C12N15/62;C12P21/02 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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