发明名称 |
RECOMBINANT PROTEIN PRODUCTION IN HETEROLOGOUS SYSTEMS |
摘要 |
Isolated polynucleotides are disclosed which increase the efficiency of gene expression in a heterologous cell. The polynucleotide sequences which encode polypeptides are adapted such that the average rate of translation of the first at least about 30 amino acids is slower by at least two fold than the average rate of translation of the remaining amino acids of the polypeptide.
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申请公布号 |
US2012329091(A1) |
申请公布日期 |
2012.12.27 |
申请号 |
US201113582472 |
申请日期 |
2011.01.25 |
申请人 |
PILPEL YITZHAK;TULLER TAMIR;NAVON SIVAN;RUBINSTEIN MENACHEM;YEDA RESEARCH AND DEVELOPMENT CO., LTD. |
发明人 |
PILPEL YITZHAK;TULLER TAMIR;NAVON SIVAN;RUBINSTEIN MENACHEM |
分类号 |
C12P21/00;C12N15/11;C12N15/12;C12N15/13;C12N15/16;C12N15/17;C12N15/20;C12N15/29;C12N15/31;C12N15/56;C12N15/63 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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