METHOD FOR ACTIVATION OF SPECIFIC PERIPHERAL BLOOD MONONUCLEAR CELLS
摘要
The invention discloses a method for the preparation of stimulated cytotoxic (aß and ?d) T cells and NK cells, comprising the following steps: - providing a preparation containing CD1b-positive (CD1b+) antigen presenting cells and responder lymphocytes (T cells and NK cells), - stimulating the preparation of CD1b+ antigen presenting cells and responder lymphocytes with an anti-CD1b antibody and interleukin 2 (IL-2), and - cultivating the stimulated CD1b+ antigen presenting cells and responder lymphocytes in a culture medium to obtain stimulated cytotoxic (aß and ?d) T cells and NK cells.
申请公布号
WO2012175598(A1)
申请公布日期
2012.12.27
申请号
WO2012EP61943
申请日期
2012.06.21
申请人
ONCOTYROL - CENTER FOR PERSONALIZED CANCER MEDICINE GMBH;THURNHER, MARTIN;GRUENBACHER, GEORG;NUSSBAUMER, OLIVER
发明人
THURNHER, MARTIN;GRUENBACHER, GEORG;NUSSBAUMER, OLIVER