发明名称 Antibodies capable to selectively detect prion PrP Sc isoforms
摘要 The present invention pertains to novel antibodies directed to the C-terminal part of the PrP<Sc> isoform of prions. In particular, the present invention pertains to the use of such antibodies in the diagnosis of bovine spongiform encephalopathy (BSE) and the new variant form of Creutzfeld Jacobs Disease (vCJD). In addition, the present invention relates to the peptide recognized by the antibodies and its use in the immunization and/or treatment of BSE, CJD, vCJD and other TSE related diseases.
申请公布号 EP1158003(B2) 申请公布日期 2012.12.26
申请号 EP20000111108 申请日期 2000.05.23
申请人 BLOOD TRANSFUSION CENTRE OF SLOVENIA 发明人 CURIN-SERBEC, DR.
分类号 C07K16/18;G01N33/53;A61K39/00;A61K39/395;A61P25/28;C07K7/08;C07K14/47;C07K16/42;C12N5/10;C12N5/20;C12N15/02;C12P21/08;G01N33/569;G01N33/577 主分类号 C07K16/18
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