发明名称 |
ARYL CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS FOR TREATEMNT OF PAIN |
摘要 |
<p>The present invention provides compounds that are inhibitors of voltage-gated sodium channels (Nav), in particular Nav 1.7, and are therefore useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.</p> |
申请公布号 |
EP2536689(A1) |
申请公布日期 |
2012.12.26 |
申请号 |
EP20110706106 |
申请日期 |
2011.02.16 |
申请人 |
AMGEN INC. |
发明人 |
BREGMAN, HOWARD;BUCHANAN, JOHN, L.;CHAKKA, NAGASREE;DIMAURO, ERIN, F.;DU, BINGFAN;NGUYEN, HANH, NHO;ZHENG, XIAO, MEI |
分类号 |
C07D213/74;A61K31/4427;A61K31/505;A61K31/506;A61K31/53;A61P29/00;C07D239/48;C07D251/48;C07D401/04;C07D403/04;C07D471/10 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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