| 发明名称 |
MUTANTS OF FRANCISELLA TULARENSIS AND USES THEREOF |
| 摘要 |
<p>The present invention relates to a mutant Francisella tularensis strain comprising an inactivated clpB gene and compositions comprising such mutant. Methods of producing the mutant are also described. The present invention also encompasses a method of conferring immunity against F. tularensis in a host, comprising administering the described mutant F. tularensis strain.</p> |
| 申请公布号 |
EP2424974(A4) |
申请公布日期 |
2012.12.26 |
| 申请号 |
EP20100769182 |
申请日期 |
2010.04.23 |
| 申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
CONLAN, JOSEPH WAYNE;SJOSTEDT, ANDERS |
| 分类号 |
C12N1/21;A61K35/74;A61K39/02;A61P31/04;A61P37/04;C12N1/20;C12N15/00;C12N15/31 |
主分类号 |
C12N1/21 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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