发明名称 |
Prevention/treatment of ichthyosis vulgaris, atopy and other disorders |
摘要 |
The present invention relates to the prevention/treatment of ichthyosis vulgaris (IV), atopy and potentially other disorders associated with loss-of-function mutations in the filaggrin gene sequence. The prevention/therapy is based on the use of agents which enable the host's translational machinery to read through a nonsense mutation found in a mutant allele of the filaggrin gene. |
申请公布号 |
US8338386(B2) |
申请公布日期 |
2012.12.25 |
申请号 |
US20070161534 |
申请日期 |
2007.01.17 |
申请人 |
MCLEAN WILLIAM HENRY IRWIN;SMITH FRANCES JANE DOROTHY;UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE |
发明人 |
MCLEAN WILLIAM HENRY IRWIN;SMITH FRANCES JANE DOROTHY |
分类号 |
A61K31/7105;A61K31/7008;A61K31/702;A61K31/7036;C07H5/06;C07H15/20;C07H15/22;C07H15/222;C07H15/224;C07H15/226;C07H15/228;C07H15/232;C07H15/234;C07H21/02 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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