| 发明名称 |
(2,5-dioxoimidazolidin-i-yl)-n-hydroxy-acetamides as metalloproteinase inhibitors |
| 摘要 |
The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are among other things useful for the treatment of obstructive airway diseases, such as chronic obstructive pulmonary disease (COPD). |
| 申请公布号 |
US8338471(B2) |
申请公布日期 |
2012.12.25 |
| 申请号 |
US201113222883 |
申请日期 |
2011.08.31 |
| 申请人 |
WALLBERG HANS;XU MING-HUA;LIN GUO-QIANG;LEI XIN-SHENG;SUN PIAOYANG;PARKES KEVIN;JOHNSON TONY;SAMUELSSON BERTIL;MEDIVIR AB |
发明人 |
WALLBERG HANS;XU MING-HUA;LIN GUO-QIANG;LEI XIN-SHENG;SUN PIAOYANG;PARKES KEVIN;JOHNSON TONY;SAMUELSSON BERTIL |
| 分类号 |
A61K31/4166;C07D233/02 |
主分类号 |
A61K31/4166 |
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