发明名称 Anti-CD33 antibodies and methods for treatment of acute myeloid leukemia using the same
摘要 The present invention relates to antibodies that bind CD33. More particularly, the invention relates to anti-CD33 antibodies, fragments and homologues of these antibodies, humanized and resurfaced versions of these antibodies, functional equivalents and improved versions of these antibodies, immunoconjugates and compositions comprising these antibodies, and the uses of same in diagnostic, research and therapeutic applications. The invention also relates to a polynucleotide encoding these antibodies, vectors comprising the polynucleotides, host cells transformed with polynucleotides and methods of producing these antibodies.
申请公布号 US8337855(B2) 申请公布日期 2012.12.25
申请号 US201113019478 申请日期 2011.02.02
申请人 HOFFEE MARY G.;TAVARES DANIEL;LUTZ ROBERT J.;IMMUNOGEN INC. 发明人 HOFFEE MARY G.;TAVARES DANIEL;LUTZ ROBERT J.
分类号 A61K38/00;A61K;A61K39/395;A61K39/40;A61K39/42;A61K39/44;C07H21/04;C07K16/28;C07K16/46;C12N5/06;C12N5/16;C12N15/00;G01N33/574 主分类号 A61K38/00
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