发明名称 |
Selective ablation of pain-sensing neurons by administration of a vanilloid receptor agonist |
摘要 |
The present invention provides methods and kits for the selective ablation of pain-sensing neurons. The methods comprise administration of a vanilloid receptor agonist to a ganglion in an amount that causes death of vanilloid receptor-bearing neurons. Accordingly, the present invention provides methods of controlling pain and inflammatory disorders that involve activation of vanilloid receptor-bearing neurons.
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申请公布号 |
US8338457(B2) |
申请公布日期 |
2012.12.25 |
申请号 |
US20100776304 |
申请日期 |
2010.05.07 |
申请人 |
IADAROLA MICHAEL J.;OLAH ZOLTAN;KARAI LASZLO;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HUMAN SERVICES |
发明人 |
IADAROLA MICHAEL J.;OLAH ZOLTAN;KARAI LASZLO |
分类号 |
A01N43/40;A01N43/02;A61K31/16;A61K31/335;A61K31/445;A61K36/81 |
主分类号 |
A01N43/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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