发明名称 |
Treatment of Parkinson's disease and enhancement of dopamine signal using PDE 10 inhibitor |
摘要 |
The present invention relates to a therapeutic or prophylactic method for treating Parkinson's disease by administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to a pharmaceutical composition for treatment or prophylaxis of Parkinson's disease comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity. Moreover, the present invention relates to a method for enhancing dopamine signal in the brain, which comprises administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to pharmaceutical composition for enhancing dopamine signal in brain comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity.
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申请公布号 |
US8338420(B1) |
申请公布日期 |
2012.12.25 |
申请号 |
US20090647880 |
申请日期 |
2009.12.28 |
申请人 |
KOTERA JUN;SASAKI TAKASHI;KITAZAWA TAKEO;ISHII TAKETOSHI;MORIMOTO HIROSHI;YAMADA HARUTAMI;MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
KOTERA JUN;SASAKI TAKASHI;KITAZAWA TAKEO;ISHII TAKETOSHI;MORIMOTO HIROSHI;YAMADA HARUTAMI |
分类号 |
A61K31/50;A61K31/40;C07D471/22 |
主分类号 |
A61K31/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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