PREPARATION METHOD OF DIHYDROINDENE AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS THEREOF AND USE AS PROTEIN KINASE INHIBITOR

摘要

Disclosed is a compound of Formula I or a pharmaceutically acceptable salt, wherein the substituents are as described within the specification. An examples of a compound of Formula I is 1-(4-Methylpiperazin-1-yl)-N-(4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl)-2,3-dihydro-1H-inden-5-carboxamide. Further disclosed is a pharmaceutical composition comprising a compound of Formula I, and the use of said compound in the manufacture of medicament for treating diseases or disorders associated with protein kinase activity or abnormality of cell proliferation.