发明名称 N,N,N-TRIALKYLPOLYMERS, METHODS OF THEIR PREPARATION AND USES THEREOF
摘要 There is provided a method for the preparation of an N,N,N-trialkylaminopolymer having one or more unsubstituted heteroatoms different from nitrogen atom. The method comprises a first step of alkylating an aminopolymer to produce an N,N-dialkylaminopolymer, wherein substantially no N,N,N- trialkylaminopolymer is produced; and a second step of alkylating the N,N-diaminopolymer to produce the N,N,N-trialkylaminopolymer. The N,N,N-trialkylaminopolymer is produced with a satisfactory degree of quaternization and with only a low percentage of the unsubstituted heteroatoms alkylated. The N,N,N- trialkylaminopolymer can be an N,N,N-trialkylaminopolysaccharide or an N,N,N-trialkylchitosan such as N,N,N-trimethylchitosan.
申请公布号 CA2869821(A1) 申请公布日期 2012.12.20
申请号 CA20122869821 申请日期 2012.06.13
申请人 RIVAL, SOCIETE EN COMMANDITE 发明人 GAGNON, JONATHAN
分类号 C08B37/08;A61K8/73;A61K31/722;A61K47/36;A61P3/06;A61P17/02 主分类号 C08B37/08
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