发明名称 |
TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS |
摘要 |
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
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申请公布号 |
US2012321555(A1) |
申请公布日期 |
2012.12.20 |
申请号 |
US201213460622 |
申请日期 |
2012.04.30 |
申请人 |
SCHENK DALE B.;SEUBERT PETER A.;WALL JONATHAN;SALDANHA JOSE W.;UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION;ELAN PHARMACEUTICALS, INC. |
发明人 |
SCHENK DALE B.;SEUBERT PETER A.;WALL JONATHAN;SALDANHA JOSE W. |
分类号 |
A61K49/00;A61B5/055;A61K49/04;A61K51/10 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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地址 |
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