COMPOSITIONS USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to compounds of formula I:where R, R, R, R, R, x and z are determined in items of the invention formula, useful as inhibitors of voltage-gated sodium channels.EFFECT: invention claims pharmaceutically acceptable compositions, which contain said compounds and methods of applying such compositions for treatment of various diseases.76 cl, 3 tbl