RUTAECARPINE DERIVATIVES FOR ACTIVATING CYP1A2 IN A SUBJECT

摘要

The teachings provided herein generally relate to compositions comprising rutaecarpine derivatives that activates CYP1 A2 through enzyme induction. The uses for such a derivative can include removing caffeine from a subject, improving sleep, treating insomnia, treating caffeine toxicity, treating caffeine addiction and withdrawal symptoms, and the like. Caffeine is just one example of a substrate that can be removed using the derivatives taught herein, and other examples, including theophylline, are provided herein.