| 发明名称 |
PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS |
| 摘要 |
The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated. |
| 申请公布号 |
US2012322791(A1) |
申请公布日期 |
2012.12.20 |
| 申请号 |
US201113520274 |
申请日期 |
2011.01.18 |
| 申请人 |
SIDDIQUI M. ARSHAD;NAN YANG;PATEL MEHUL F.;REDDY PANDURANGA ADULLA P.;MANSOOR UMAR FARUK;MENG ZHAOYANG;VITHARANA LALANTHI DILRUKSHI;ZHAO LIANYUN;MANDAL AMIT K.;LIU DUAN;TANG SHUYI;MCRINER ANDREW;BELANGER DAVID B.;CURRAN PATRICK J.;DAI CHAOYANG;ANGELES ANGIE R.;YANG LIPING;DANIELS MATTHEW HERSH |
发明人 |
SIDDIQUI M. ARSHAD;NAN YANG;PATEL MEHUL F.;REDDY PANDURANGA ADULLA P.;MANSOOR UMAR FARUK;MENG ZHAOYANG;VITHARANA LALANTHI DILRUKSHI;ZHAO LIANYUN;MANDAL AMIT K.;LIU DUAN;TANG SHUYI;MCRINER ANDREW;BELANGER DAVID B.;CURRAN PATRICK J.;DAI CHAOYANG;ANGELES ANGIE R.;YANG LIPING;DANIELS MATTHEW HERSH |
| 分类号 |
A61K31/519;A61K31/5377;A61K31/5386;A61K31/547;A61K31/55;A61P35/00;C07D471/08;C07D487/04;C07D487/08;C07D491/147;C07D498/08;C07D513/08 |
主分类号 |
A61K31/519 |
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