摘要 |
<p>Methods of mass spectrometry are disclosed comprising providing a flight region along which a potential profile is maintained such that ions travel therethrough towards, for example, a detector or fragmentation device. The potential of a first length L3 of the flight region is then changed from a first potential V3 to a second potential V6 whilst at least some ions are travelling therein. The changed potential provides a first potential difference X through which the ions are accelerated when they exit the length L3 of the flight region. This increases the kinetic energy of the ions prior to them reaching the detector or fragmentation cell. The potentials of the first and further lengths of the flight region, and said potential differences created at the exits thereof, may be changed through the application of RF (see Figs 3 & 4) and/or DC voltages to electrodes forming the flight region.</p> |