发明名称 |
Polynucleotides comprising intercalating entities |
摘要 |
Provided are nucleic acid compositions modified with intercalating aromatic compounds attached directly or indirectly through a linker arm thereto. Modifications to the nucleotides or to the oligo- or polynucleotides involve the pentosyl moieties, the abasic moieties (without a base) and the base moieties. Useful property changes are effected and can be measured or detected when such modified nucleic acids compositions have hybridized specifically to target nucleic acids. |
申请公布号 |
US8334370(B1) |
申请公布日期 |
2012.12.18 |
申请号 |
US19920956566 |
申请日期 |
1992.10.05 |
申请人 |
STAVRIANOPOULOS JANNIS;RABBANI ELAZAR;ENZO BIOCHEM, INC. |
发明人 |
STAVRIANOPOULOS JANNIS;RABBANI ELAZAR |
分类号 |
C07H21/00;G01N21/78;A61K31/7115;A61K48/00;A61P35/00;C07H19/067;C07H19/073;C07H19/14;C07H19/167;C07H19/173;C07H21/02;C07H21/04;C12N15/09;C12Q1/68;G01N21/76;G01N33/50;G01N33/58 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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