发明名称 TETRAHYDROISOQUINOLINE DERIVATIVE
摘要 The present invention relates to a compound or a pharmacologically acceptable salt thereof having an excellent DGAT inhibitory effect and feeding suppressant effect. The present invention provides a compound represented by the general formula (I), or pharmacologically acceptable salt thereof: (see formula I) [wherein, R1 represents a phenylaminocarbonyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group A, a benzoxazol-2-yl group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group A, or the like; R2 independently represents a C1-C6 alkyl group; R3 represents a group represented by the formula -C(=O)-O-R4 or the like; R4 represents a hydrogen atom, a C1-C6 alkyl group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group B, or the like; X represents an oxygen atom, a methylene group, or a group represented by the formula -NH-, or the like; L represents a single bond, a methylene group, or the like;...... represents a single bond or a double bond; m represents 1 or 2; n represents an integer of 0 to 5; Substituent Group A represents a halogen atom, a C1-C6 alkyl group, a C1-C6 halogenated alkyl group, a C1-C6 alkoxy group, or the like; and Substituent Group B represents a C3-C6 cycloalkyl group, a phenyl group, a carboxyl group, or the like].
申请公布号 CA2719721(C) 申请公布日期 2012.12.18
申请号 CA20092719721 申请日期 2009.03.24
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 UTO, YOSHIKAZU;KARASAWA, HIROSHI;TAKAISHI, KIYOSUMI
分类号 C07D217/06;A61K31/472;A61K31/4725;A61P1/16;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P15/08;A61P27/12;A61P29/00;A61P43/00;C07D401/12;C07D413/12;C07D417/12 主分类号 C07D217/06
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