| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for screening a therapeutic agent for cartilage diseases by finding out a molecule relating to cartilage differentiation, as well as modified cartilage cells usable for treating the cartilage diseases. <P>SOLUTION: There are provided a method for screening a material having action for increasing a cartilage mass and/or action for normalizing cartilage cell differentiation, characterized in using salt-inducible kinase 3, and the modified cartilage cells used for improving cartilage mass-decreasing diseases and/or cartilage growth inhibiting diseases, and suppressed or enhanced in the expression or function of salt-inducible kinase 3 gene. <P>COPYRIGHT: (C)2013,JPO&INPIT |
