摘要 |
<P>PROBLEM TO BE SOLVED: To provide an isolated anti-EphB4 antibody. <P>SOLUTION: The isolated anti-EphB4 antibody comprises such as the following: (a) following: (i) HVR-L1 comprising sequence A1-A11, wherein A1-A11 is RASQDVSTAVA (SEQ ID NO: 9); (ii) HVR-L2 comprising sequence B1-B7, wherein B1-B7 is SASFLYS (SEQ ID NO:11); (iii) HVR-L3 comprising sequence C1-C9, wherein C1-C9 is QESTTTPPT (SEQ ID NO:15); and (iv) HVR-H1 comprising sequence D1-D10, wherein D1-D10 is GFSISNYYLH (SEQ ID NO:2). <P>COPYRIGHT: (C)2013,JPO&INPIT |