发明名称 ANTI-EPHB4 ANTIBODY AND METHOD USING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide an isolated anti-EphB4 antibody. <P>SOLUTION: The isolated anti-EphB4 antibody comprises such as the following: (a) following: (i) HVR-L1 comprising sequence A1-A11, wherein A1-A11 is RASQDVSTAVA (SEQ ID NO: 9); (ii) HVR-L2 comprising sequence B1-B7, wherein B1-B7 is SASFLYS (SEQ ID NO:11); (iii) HVR-L3 comprising sequence C1-C9, wherein C1-C9 is QESTTTPPT (SEQ ID NO:15); and (iv) HVR-H1 comprising sequence D1-D10, wherein D1-D10 is GFSISNYYLH (SEQ ID NO:2). <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012245009(A) 申请公布日期 2012.12.13
申请号 JP20120195216 申请日期 2012.09.05
申请人 GENENTECH INC 发明人 WU YAN;YAN MINHONG
分类号 C12N15/09;A61K39/395;A61K45/00;A61K45/06;A61P9/00;A61P35/00;A61P43/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08;G01N33/53 主分类号 C12N15/09
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