发明名称 PHARMACEUTICAL SALT AND POLYMORPH OF N- (5-CHLORO-2-PYRIDINYL)-2-[[4-[(DIMETHYLAMINO)IMINOMETHYL]BENZOYL]AMINO]-5-METHOXY-BENZAMIDE, FACTOR XA INHIBITOR
摘要 <P>PROBLEM TO BE SOLVED: To provide a novel pharmaceutical salt and polymorph of a factor Xa inhibitor. <P>SOLUTION: The salt includes a compound of formula (I) and an acid that has activity against mammalian factor Xa. A method for producing the compound of formula (I) is also provided. The acid is selected from the group consisting of hydrochloric acid, lactic acid, maleic acid, phenoxyacetic acid, propionic acid, succinic acid, adipic acid, ascorbic acid, camphoric acid, gluconic acid, phosphic acid, tartaric acid, citric acid, methanesulfonic acid, fumaric acid, glycolic acid, naphthalene-1,5-disulfonic acid, gentisic acid and benzenesulfonic acid. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012246323(A) 申请公布日期 2012.12.13
申请号 JP20120204757 申请日期 2012.09.18
申请人 MILLENNIUM PHARMACEUTICALS INC 发明人 GRANT CRAIG;KANTER JAMES P;LANGLANDS GRAEME
分类号 C07D213/75;A61K9/08;A61K9/20;A61K9/48;A61K31/44;A61P7/02;A61P9/00;A61P9/10;A61P43/00 主分类号 C07D213/75
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