发明名称 |
HALOGEN-ALKYL-1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS |
摘要 |
The present invention provides compounds of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes. |
申请公布号 |
WO2012168164(A1) |
申请公布日期 |
2012.12.13 |
申请号 |
WO2012EP60457 |
申请日期 |
2012.06.04 |
申请人 |
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A;WOLTERING, THOMAS |
发明人 |
WOLTERING, THOMAS |
分类号 |
C07D413/12;A61K31/5355;A61P25/28 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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