发明名称 Modulation of Cell Barrier Dysfunction
摘要 The invention provides prophylactic and therapeutic methods for administering a μ-opioid receptor antagonist, e.g., N-methylnaltrexone or a salt thereof, to treat cell barrier diseases and disorders, such as endothelial and epithelial cell barrier diseases and disorders, e.g., inflammatory bowel disease. Methods of reducing the symptoms of inflammatory bowel disease and the risk of developing inflammatory bowel disease are also provided.
申请公布号 US2012316190(A1) 申请公布日期 2012.12.13
申请号 US201213483932 申请日期 2012.05.30
申请人 ALVERDY JOHN C.;MOSS JONATHAN;LINGEN MARK W.;SINGLETON PATRICK A.;GARCIA JOE G.N.;THE UNIVERSITY OF CHICAGO 发明人 ALVERDY JOHN C.;MOSS JONATHAN;LINGEN MARK W.;SINGLETON PATRICK A.;GARCIA JOE G.N.
分类号 A61K31/485;A61P1/00 主分类号 A61K31/485
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