Heterocyclic sulfone mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

摘要

Heterocyclic sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.