发明名称 |
Imidazole-2,4-Dione Inhibitors of Casein Kinase 1 |
摘要 |
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), the TGF&bgr; pathway and/or the Wnt pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), the TGF&bgr; pathway and/or the Wnt pathway. |
申请公布号 |
US2012316155(A1) |
申请公布日期 |
2012.12.13 |
申请号 |
US201113577535 |
申请日期 |
2011.02.17 |
申请人 |
BALDINO CARMEN M.;CASERTA JUSTIN L.;LEE CHEE-SENG;NICEWONGER ROBERT B.;JASCO PHARMACEUTICALS, LLC |
发明人 |
BALDINO CARMEN M.;CASERTA JUSTIN L.;LEE CHEE-SENG;NICEWONGER ROBERT B. |
分类号 |
A61K31/506;A61K31/497;A61K31/5377;A61K31/551;A61P3/08;A61P3/10;A61P19/08;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P35/00;C07D401/14;C07D403/06;C07D403/14;C07D405/14;C07D409/14;C07D413/14 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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