发明名称 |
SYNTHETIC DIBLOCK COPOLYPEPTIDE HYDROGELS FOR USE IN THE CENTRAL NERVOUS SYSTEM |
摘要 |
This invention relates, e.g., to a composition suitable for administration to the central nervous system (CNS), comprising a block copolypeptide hydrogel, which comprises a biologically active material that is mixed with the hydrogel or that is attached to the polypeptide chain of the hydrogel, wherein the composition is suitable for administration to the CNS. Also disclosed are methods of making and using compositions of the invention as depots or as scaffolds for cell migration, and pharmaceutical compositions and kits for implementing methods of the invention. |
申请公布号 |
EP2400974(A4) |
申请公布日期 |
2012.12.12 |
申请号 |
EP20100744302 |
申请日期 |
2010.02.18 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DEMING, TIMOTHY, J.;SOFRONIEW, MICHAEL, V.;YANG, CHU-YA;SONG, BINGBING;AO, YAN |
分类号 |
A61K9/06;A61K9/113;A61K9/127;A61K31/7004;A61K31/7088;A61K31/715;A61K31/787;A61K38/00;A61K47/34;A61K47/48;A61L27/22;A61L27/52;A61L27/54 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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