发明名称 Staphyloccal immunogens
摘要 The S. aureus Ser-Asp rich fibrinogen/bone sialoprotein-binding protein contains three CnaB domains, and that the third of these provides significant protection against S. aureus infection. Thus a useful S. aureus vaccine can include a SdrE CnaB domain. Furthermore, the SdrE protein has been shown to be relatively resistant to trypsin digestion, which could be connected to the observation that SdrE contains an isopeptide bond within the third CnaB domain.
申请公布号 GB201219420(D0) 申请公布日期 2012.12.12
申请号 GB20120019420 申请日期 2012.10.29
申请人 NOVARTIS AG 发明人
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