发明名称 |
DIAGNOSTIC AND PROGNOSTIC ASSAY FOR BREAST CANCER |
摘要 |
The invention relates to the finding that T cell protein tyrosine phosphatase (TCPTP) has a tumour suppressor function. In one particular application, the invention provides a method of diagnosis and/or prognosis of cancer in a subject involving the assessment, in a suitable body sample, of any lack or reduction of TCPTP protein and/or Ptpn2 gene expression. The invention also provides a method of treating or preventing cancer in a subject involving administering to a subject an agent for modulating the activity of TCPTP. |
申请公布号 |
EP2531616(A1) |
申请公布日期 |
2012.12.12 |
申请号 |
EP20110739266 |
申请日期 |
2011.02.03 |
申请人 |
MONASH UNIVERSITY |
发明人 |
TIGANIS, TONY;SHIELDS, BENJAMIN, JAMES;MCLEAN, CATRIONA, ANN;SUTHERLAND, ROBERT |
分类号 |
C12Q1/68;A61K38/18;A61K48/00;A61P35/00;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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