| 发明名称 |
Macrocyclic compounds useful as pharmaceuticals |
| 摘要 |
The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1-R11, t, X, Y, Z, and n are as defined herein.
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| 申请公布号 |
US8329742(B2) |
申请公布日期 |
2012.12.11 |
| 申请号 |
US20100839873 |
申请日期 |
2010.07.20 |
| 申请人 |
BOIVIN ROCH;CHIBA KENICHI;CHOW JESSE;DU HONG;EGUCHI YOSHIHITO;FUJITA MASANORI;GOTO MASAKI;GUSOVSKY FABIAN;HARMANGE JEAN-CHRISTOPHE;INOUE ATSUSHI;JIANG YIMIN;KAWADA MEGUMI;KAWAI TAKATOSHI;KAWAKAMI YOSHIYUKI;KIMURA AKIFUMI;KOTAKE MAKOTO;KUBOI YOSHIKAZU;LEMELIN CHARLES-ANDRE;LI XIANG-YI;MATSUSHIMA TOMOHIRO;MIZUI YOSHIHARU;MURAMOTO KENZO;SAKURAI HIDEKI;SHEN YONG-CHUN;SHIROTA HIROSHI;SPYVEE MARK;TANAKA ISAO;WANG JOHN (YUAN);YAMAMOTO SATOSHI;YONEDA NAOKI;EISAI CO., LTD. |
发明人 |
BOIVIN ROCH;CHIBA KENICHI;CHOW JESSE;DU HONG;EGUCHI YOSHIHITO;FUJITA MASANORI;GOTO MASAKI;GUSOVSKY FABIAN;HARMANGE JEAN-CHRISTOPHE;INOUE ATSUSHI;JIANG YIMIN;KAWADA MEGUMI;KAWAI TAKATOSHI;KAWAKAMI YOSHIYUKI;KIMURA AKIFUMI;KOTAKE MAKOTO;KUBOI YOSHIKAZU;LEMELIN CHARLES-ANDRE;LI XIANG-YI;MATSUSHIMA TOMOHIRO;MIZUI YOSHIHARU;MURAMOTO KENZO;SAKURAI HIDEKI;SHEN YONG-CHUN;SHIROTA HIROSHI;SPYVEE MARK;TANAKA ISAO;WANG JOHN (YUAN);YAMAMOTO SATOSHI;YONEDA NAOKI |
| 分类号 |
A61K31/355;C07D491/044;A61K31/335;A61K31/36;A61K31/365;A61K31/395;A61K31/4178;A61K31/4188;A61K31/5377;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P7/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/04;A61P17/06;A61P17/16;A61P19/02;A61P19/04;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/08;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P33/06;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D267/00;C07D313/00;C07D401/12;C07D405/12;C07D491/04;C07D493/04;C07D521/00 |
主分类号 |
A61K31/355 |
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