发明名称 |
METHOD FOR DETECTION OF CAMP AND CGMP |
摘要 |
The present invention relates to an in vitro method for detecting cAMP or cGMP comprising a) contacting a mixture with a complex of a tracer and a dequencher, wherein the tracer is a fluorophore covalently linked to a cAMP quencher, and b) measuring the change in fluorescence. Furthermore, the present invention relates to the use of said method for determining the cAMP or cGMP concentration in the mixture, for determining the activity of a receptor wherein the signal transduction of the receptor comprises cAMP or cGMP and for screening of a ligand for such a receptor.
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申请公布号 |
CA2615067(C) |
申请公布日期 |
2012.12.11 |
申请号 |
CA20072615067 |
申请日期 |
2007.12.17 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ENDERLE, THILO;MATILE, HUGUES;ROTH, DORIS |
分类号 |
G01N33/566;G01N33/52;G01N33/53;G01N33/58 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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