The present invention relates to in vitro and ex vivo methods of screening for modulators, homologues, and mimetics of lethal factor mitogen activated protein kinase kinase (MAPKK) protease activity, as well as methods of treating cancer by administering LF to transformed cells.
申请公布号
CA2324379(C)
申请公布日期
2012.12.11
申请号
CA19992324379
申请日期
1999.03.31
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRE TARY, DEPARTMENT OF HEALTHAND HUMAN SERVICES
发明人
DUESBERY, NICHOLAS;WEBB, CRAIG;LEPPLA, STEPHEN;WOUDE, GEORGE VANDE
