摘要 |
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2c receptor agonists for the treatment of 5-HT2c associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety, where, R6 is -NR10R11, where R10 is substituted phenylalkyl or substituted pyridylalkyl and other substituents are as defined in the specification. |
申请人 |
ELI LILLY & COMPANY |
发明人 |
ADEVA BARTOLOME, MARTA;GALKA, CHRISTOPHER, STANLEY;MARCOS LLORENTE, ALICIA;MARTINEZ-GRAU, MARIA, ANGELES;O'TOOLE, JOHN, CUNNINGHAM;REINHARD, MATTHEW, ROBERT;BRINER, KARIN;CASES-THOMAS, MANUEL, JAVIER;MAZANETZ, MICHAEL, PHILIP;RATHMELL, RICHARD, EDMUND;SAPMAZ, SELMA;WILLIAMS, ANDREW, CAERWYN |