发明名称 METHOD OF ADJUVANT THERAPY OF STOMACH CANCER
摘要 FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to oncology, and may be used in integrated treatment of stomach cancer. That is ensured by a surgical intervention to place a microirrigator into an abdominal cavity. Then 4 weeks after the surgery, blood 300 ml is taken on the first day to be centrifuged and to recover autoplasma. Autoplasma and chemopreparations are placed into a first flask, autoplasma - into second and third flasks, blood corpuscles and chemopreparations - into a forth force. The 2and 3flasks are frozen, the 1and 4flasks are separately incubated for 40 minutes at 37°C. The incubated blood corpuscles and chemopreparations from the 4flask are introduced intravenously drop-by-drop. Autoplasma and chemopreparations from the 1flask are introduced intraperitoneally through the microirrigator. It is followed by 1 session of radiation therapy on the abdominal cavity at single dose 2 Gy. On the 2and 4therapeutic days, only sessions of radiation therapy are applied. On the 3and 5days, the sessions of radiation therapy are preceded by freezing one flask with autoplasma added with chemopreparations, and the flasks are incubated for 40 minutes at 37°C. Then autoplasma and chemopreparations are introduced intraperitoneally through the microirrgator, and the session of radiation therapy is conducted. On the 6and 7days, a pause is made. Starting from 8th and 15th days, a five-day therapeutic course is repeated.EFFECT: method enables reducing rate of metastases in the peritoneum caused by stomach cancer and increasing survival rate of the patients due to combined surgical and chemoradiation therapy in a certain mode.2 ex
申请公布号 RU2468837(C2) 申请公布日期 2012.12.10
申请号 RU20100150390 申请日期 2010.12.08
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "ROSTOVSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ ONKOLOGICHESKIJ INSTITUT" MINISTERSTVA ZDRAVOOKHRANENIJA ISOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII 发明人 KIT OLEG IVANOVICH;GEVORKJAN JURIJ ARTUSHEVICH;SOLDATKINA NATAL'JA VASIL'EVNA;DZHABAROV FARKHAD RASIMOVICH;ZHUZHELENKO IRINA ALEKSANDROVNA
分类号 A61N5/00;A61K31/513;A61K35/16;A61M1/36;A61P35/00 主分类号 A61N5/00
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