发明名称 METHOD FOR DETECTION OF IMMUNE RECONSTITUTION INFLAMMATORY DISEASE IN PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS AND HIV INFECTION WITH UNDERLYING HIGH-ACTIVE ANTIRETROVIRAL THERAPY
摘要 FIELD: medicine.SUBSTANCE: invention refers to medicine, namely phthisiology and infectious diseases, and may be used for detection of immune reconstitution inflammatory disease in the patients suffering drug-resistant tuberculosis and HIV infection. That is ensured by clinical assessment of the patient's state with underlying high-active antiretroviral therapy (HAART). If observing general loss of condition, temperature rise, progression of inflammatory process in the involved organs, prednisolone 0.5 mg/kg therapy is prescribed once a day for 10-12 days. The therapeutic course of prednisolone is followed by another clinical assessment, and if observing normalised temperature, regression of inflammatory process, general amelioration, the presence of immune reconstitution disease is stated.EFFECT: use of the given method enables higher accuracy of detection of immune reconstitution disease in the patients with drug-resistant tuberculosis and HIV infection with underlying HAART.2 ex
申请公布号 RU2468801(C1) 申请公布日期 2012.12.10
申请号 RU20110131614 申请日期 2011.07.27
申请人 GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "SANKT-PETERBURGSKAJA GOSUDARSTVENNAJA MEDITSINSKAJA AKADEMIJA MECHNIKOVA" MINISTERSTVA ZDRAVOOKHRANENIJA I SOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII 发明人 PANTELEEV ALEKSANDR MIKHAJLOVICH
分类号 A61K31/56;A61P37/00 主分类号 A61K31/56
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