发明名称 |
METHODS FOR TREATING DISEASES |
摘要 |
The present invention relates to methods of modulating the level of inducible nitric oxide synthase (iNOS) in a cell which comprises administering to the cell a compound which modulates binding of SPRY domain-containing SOCS box protein (SSB) to iNOS, and/or a compound which modulates SSB activity in the cell. Further provided are methods of treating or preventing disease in a subject by modulating the level of iNOS in a cell, as well as compounds which modulate binding of SSB to iNOS and compounds which modulate SSB activity.
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申请公布号 |
US2012308570(A1) |
申请公布日期 |
2012.12.06 |
申请号 |
US201013319090 |
申请日期 |
2010.05.06 |
申请人 |
KOLESNIK TATIANA;KUANG ZHIHE;LEWIS ROWENA SUE;NICHOLSON SANDRA ELAINE;NORTON RAY |
发明人 |
KOLESNIK TATIANA;KUANG ZHIHE;LEWIS ROWENA SUE;NICHOLSON SANDRA ELAINE;NORTON RAY |
分类号 |
A61K38/17;A61K38/08;A61K39/395;A61P11/00;A61P11/06;A61P29/00;C07K7/08;C07K14/435;C07K16/18;C12N5/071;G01N21/55;G01N24/08;G01N33/566;G01N33/573 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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