发明名称 NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: (I) where R1, R2, R3, R4, and R5 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 CA2835216(A1) 申请公布日期 2012.12.06
申请号 CA20122835216 申请日期 2012.05.18
申请人 THERAVANCE, INC. 发明人 GENDRON, ROLAND;HUGHES, ADAM D.
分类号 C07D231/14;A61K31/415;A61K31/4155;A61P9/00;A61P9/12;C07D401/04;C07D401/06;C07D403/04;C07D403/06;C07D403/12;C07D405/04;C07D405/12;C07D413/04;C07D413/06 主分类号 C07D231/14
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