| 摘要 |
The present invention relates to a method for the in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity (eg a monoacylglycerol hydrolase such as Rv0183, a phospholipase such as Rv3452, Rv3802c, PlcA, PlcB, PlcC or PlcD, the lipase Rv1984c, or a triacylglycerol hydrolase, such as LipY), and a step of detecting the presence of specific activated lymphocytes. |
| 申请人 |
UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES;UNIVERSITE MONTPELLIER I;CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;TUAILLON, EDOUARD;RUBBO, PIERRE-ALAIN;CANAAN, STEPHANE;KREMER, LAURENT;NAGOT, NICOLAS;VAN DE PERRE, PHILIPPE;VENDRELL, JEAN-PIERRE |
发明人 |
TUAILLON, EDOUARD;RUBBO, PIERRE-ALAIN;CANAAN, STEPHANE;KREMER, LAURENT;NAGOT, NICOLAS;VAN DE PERRE, PHILIPPE;VENDRELL, JEAN-PIERRE |
