发明名称 |
SINGLE-SHOT FULL-FIELD REFLECTION PHASE MICROSCOPY |
摘要 |
The present invention relates to a full-field reflection phase microscope. In a preferred embodiment, the invention can combine low-coherence interferometry and off-axis digital holographic microscopy (DHM). The reflection-based DHM provides highly sensitive and a single-shot imaging of cellular dynamics while the use of low coherence source provides a depth-selective measurement. A preferred embodiment of the system uses a diffraction grating in the reference arm to generate an interference image of uniform contrast over the entire field-of-view albeit low-coherence light source. With improved path-length sensitivity, the present invention is suitable for full-field measurement of membrane dynamics in live cells with sub-nanometer-scale sensitivity.
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申请公布号 |
US2012307035(A1) |
申请公布日期 |
2012.12.06 |
申请号 |
US201213358254 |
申请日期 |
2012.01.25 |
申请人 |
YAQOOB ZAHID;CHOI WONSHIK;YAMAUCHI TOYOHIKO;FELD MICHAEL;FELD DAVID;HEARN ALISON;FELD JONATHAN |
发明人 |
YAQOOB ZAHID;CHOI WONSHIK;YAMAUCHI TOYOHIKO;FELD MICHAEL;FELD DAVID;HEARN ALISON;FELD JONATHAN |
分类号 |
H04N7/18 |
主分类号 |
H04N7/18 |
代理机构 |
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代理人 |
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地址 |
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