| 发明名称 |
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS |
| 摘要 |
The present invention relates to modulators of ATP-Binding Cassette (ABC) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
|
| 申请公布号 |
US2012309758(A1) |
申请公布日期 |
2012.12.06 |
| 申请号 |
US201213492164 |
申请日期 |
2012.06.08 |
| 申请人 |
SHETH URVI;FANNING LEV T.D.;NUMA MEHDI;BINCH HAYLEY;HURLEY DENNIS JAMES;ZHOU JINGLAN;HADIDA RUAH SARA S.;HAZLEWOOD ANNA R.;SILINA ALINA;VAIRAGOUNDAR RAJENDRAN;VAN GOOR FREDRICK F.;GROOTENHUIS PETER DIEDERIK JAN;BOTFIELD MARTYN C.;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
SHETH URVI;FANNING LEV T.D.;NUMA MEHDI;BINCH HAYLEY;HURLEY DENNIS JAMES;ZHOU JINGLAN;HADIDA RUAH SARA S.;HAZLEWOOD ANNA R.;SILINA ALINA;VAIRAGOUNDAR RAJENDRAN;VAN GOOR FREDRICK F.;GROOTENHUIS PETER DIEDERIK JAN;BOTFIELD MARTYN C. |
| 分类号 |
A61K31/47;A61K31/4709;A61K31/5377;A61P1/18;A61P3/00;A61P3/10;A61P11/00;A61P11/06;A61P15/08;A61P19/10;A61P25/00;A61P25/08;A61P25/16;A61P25/28;A61P27/02;A61P29/00;C07D215/56;C07D401/12;C07D413/12;C12N5/071 |
主分类号 |
A61K31/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
