发明名称 Growth Hormones With Prolonged In-Vivo Efficacy
摘要 The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there altered profile considered particular useful in therapy.
申请公布号 US2012309944(A1) 申请公布日期 2012.12.06
申请号 US201113522390 申请日期 2011.01.24
申请人 BEHRENS CARSTEN;JOHANSEN NILS LANGELAND;ANDERSEN HENRIK SUNE;NOERSKOV-LAURITSEN LEIF;BUCHARDT JENS;NOVO NORDISK HEALTH CARE AG 发明人 BEHRENS CARSTEN;JOHANSEN NILS LANGELAND;ANDERSEN HENRIK SUNE;NOERSKOV-LAURITSEN LEIF;BUCHARDT JENS
分类号 C07K14/61;C07C235/74;C07C237/22;C07C237/24;C07C237/34;C07C309/18;C07D207/452;C07D257/04;C07K5/09 主分类号 C07K14/61
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