发明名称 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
摘要 Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
申请公布号 US8324275(B2) 申请公布日期 2012.12.04
申请号 US201213446892 申请日期 2012.04.13
申请人 COOK HARRY;HAMILTON MARTHA;DANIELSON DOUGLAS;GODERSTAD COLETTE;REARDAN DAYTON T.;JAZZ PHARMACEUTICALS, INC. 发明人 COOK HARRY;HAMILTON MARTHA;DANIELSON DOUGLAS;GODERSTAD COLETTE;REARDAN DAYTON T.
分类号 A01N37/00;A61K9/06;A01N31/00;A61K9/00;A61K9/08;A61K9/10;A61K9/107;A61K31/045;A61K31/19;A61K47/02;A61K47/04;A61K47/08;A61K47/10;A61K47/12;A61K47/14;A61P25/20;A61P25/30;A61P25/32;A61P25/36 主分类号 A01N37/00
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