Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins

摘要

The present invention relates to a compound having the general Formula (I): wherein: m and n are each independently an integer from 1 to 6; X1-X3 and Y1-Y3 are each independently O or S; R1-R3 are each independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl; and R is (CH2)x-C(═O)NR′—(CH2)y-NR′R″whereas: x and y are each independently an integer from 1 to 6; and R′and R″are each independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl; and to an antibody comprising an antigen recognition region capable of specifically binding the above compound.