发明名称 |
Injectable hydrogel microspheres from aqueous two-phase system |
摘要 |
Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution. |
申请公布号 |
US8323794(B2) |
申请公布日期 |
2012.12.04 |
申请号 |
US20100855429 |
申请日期 |
2010.08.12 |
申请人 |
CHU CHIH-CHANG;ZHANG XIAN-ZHENG;WU DA-QING;CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
CHU CHIH-CHANG;ZHANG XIAN-ZHENG;WU DA-QING |
分类号 |
B32B5/16;A61K9/00;A61K9/10;A61K9/127;A61K9/16;A61K9/50;A61K38/19;B01J13/02;B32B9/00;B32B15/02;B32B17/02 |
主分类号 |
B32B5/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|