发明名称 |
Hosts and fermentation processes for cellulase production |
摘要 |
A fermentation process for the production of cellulase mixtures is provided. The process comprises providing a genetically modified host filamentous fungus that overexpresses an Xyr1 transcription factor and/or that is partially or completely deficient in expressing one or more hemicellulase enzyme. The host filamentous fungus is cultured in a medium comprising a carbon source. The carbon source contains from about 60 wt % to about 100 wt % hemicellulose-derived carbohydrate and less than 5% of a cellulase-inducing carbohydrate or contains from about 25 wt % to about 100% wt % hemicellulose-derived sugar alcohol in combination with from about 0 wt % to about 75 wt % glucose, glycerol or a combination thereof.
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申请公布号 |
US8323931(B2) |
申请公布日期 |
2012.12.04 |
申请号 |
US20090611486 |
申请日期 |
2009.11.03 |
申请人 |
GUDYNAITE-SAVITCH LORETA;HINDLE CHRISTOPHER D.;WHITE THERESA C.;IOGEN ENERGY CORPORATION |
发明人 |
GUDYNAITE-SAVITCH LORETA;HINDLE CHRISTOPHER D.;WHITE THERESA C. |
分类号 |
C12P19/14;C02F3/34;C08B37/00;C12N1/00;C12N9/42;C12P21/06;D21C1/00 |
主分类号 |
C12P19/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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