| 发明名称 |
Dual-specific IL-1α/IL-1&bgr; antibodies |
| 摘要 |
The invention provides an isolated, dual-specific antibody, or an antigen-binding portion thereof, which is specific for human IL-1αand human IL-1β. The dual specific antibodies of the invention also neutralize both human IL-1αand human IL-1β. The invention also provides domain antibodies (dAbs) specific for human IL-1αand human IL-1β.
|
| 申请公布号 |
US8324350(B2) |
申请公布日期 |
2012.12.04 |
| 申请号 |
US20070006068 |
申请日期 |
2007.12.28 |
| 申请人 |
HSIEH CHUNG-MING;MCRAE BRADFORD L.;KUTSKOVA YULIYA;MEMMOTT JOHN E.;ROGUSKA MICHAEL;TOMLINSON IAN;ENEVER CARRIE;GRANT STEVEN;TUNA MIHRIBAN;ABBOTT LABORATORIES |
发明人 |
HSIEH CHUNG-MING;MCRAE BRADFORD L.;KUTSKOVA YULIYA;MEMMOTT JOHN E.;ROGUSKA MICHAEL;TOMLINSON IAN;ENEVER CARRIE;GRANT STEVEN;TUNA MIHRIBAN |
| 分类号 |
C07K16/00 |
主分类号 |
C07K16/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
