| 发明名称 |
Compositions and methods for producing a composition |
| 摘要 |
<p>Disclosed is a composition comprising cytotoxic T lymphocyte antigen 4 immunoglobulin (CTLA4-Ig) molecules that is characterized by: (a) an average molar ratio of N-acetyl neuraminic acid (NAN A) to CTLA4-Ig molecules of from 8.0 to 11.9, and (b) less than or equal to 2.0 area percent CTLA4-Ig high molecular weight species as determined by size exclusion chromatography and spectrophotometric detection.</p> |
| 申请公布号 |
NZ597215(A) |
申请公布日期 |
2012.11.30 |
| 申请号 |
NZ20060597215 |
申请日期 |
2006.12.19 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LEISTER, KIRK, J |
| 分类号 |
A61K38/17;C07K1/16;C07K14/705 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
