发明名称 HETEROCYCLIC AMIDES AS ROCK INHIBITORS.
摘要 <p>The present invention relates to new kinase inhibitors of formula (I), more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and Respiratory diseases.</p>
申请公布号 MX2012010174(A) 申请公布日期 2012.11.30
申请号 MX20120010174 申请日期 2011.03.04
申请人 AMAKEM NV.* 发明人 DIRK LEYSEN;PETRA BLOM;OLIVIER DEFERT;NADZEYA KAVAL;SANDRO BOLAND
分类号 C07D213/75;A61K31/437;A61K31/4409;A61K31/443;A61K31/4433;A61K31/4436;A61K31/505;A61P1/00;A61P9/00;C07D239/42;C07D401/12;C07D405/12;C07D409/12;C07D471/04;C07D493/04 主分类号 C07D213/75
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